Fléole des Champs, Fléole des Prés, Mil, Phléole des Champs, Phléole des Prés, Phleum pratense, Timothy, Timothy Grass.
Phleum pratense is a plant. The pollen from this plant is used as a medicine.
One kind of Phleum pratense preparation is put under the tongue to reduce symptoms of grass pollen allergies (hay fever).
A different kind of Phleum pratense preparation is injected under the skin to reduce symptoms of hay fever and other seasonal allergies.
How does work?
Phleum pratense in very small doses is thought to desensitize the body to grass pollen allergies.
Possibly Effective for...
- Grass pollen allergies (hay fever). Specific preparations of Phleum pratense seem to significantly reduce hay fever symptoms in people with asthma. The injectable form may also reduce asthma symptoms. Some evidence suggests that giving Phleum pratense over a span of 3 years to children with grass allergy prevents development of asthma.
Phleum pratense seems safe for most adults and children aged 3-16 years. When used under the tongue, Phleum pratense can cause itching and irritation of the mouth and nose, blisters in the mouth, and runny nose. When given by injection, it can cause irritation where the needle entered the skin.
SLIDESHOW
What Is Asthma? Symptoms, Causes, and Treatments See SlideshowThe following doses have been studied in scientific research:
UNDER THE TONGUE:
- For hay fever: 75,000 units of a specific standardized Phleum pratense allergen product (Grazax, Alk Abello) daily, starting 8 weeks before grass pollen season starts and continued until it ends.
- For hay fever: 100,000 units of a specific Phleum pratense allergen product (Alutard SQ, Alk Abello) twice weekly starting 8 weeks before grass pollen season starts and continued until it ends.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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Motta A, Peltre G, Dormans JA, et al. Phleum pratense pollen starch granules induce humoral and cell-mediated immune responses in a rat model of allergy. Clin Exp Allergy 2004;34:310-4. View abstract.
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Rak S, Yang WH, Pedersen MR, Durham SR. Once-daily sublingual allergen-specific immunotherapy improves quality of life in patients with grass pollen-induced allergic rhinoconjunctivitis: a double-blind, randomised study. Qual Life Res 2007;16:191-201. View abstract.
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