Lastacaft

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 3/19/2024

Drug Summary

What Is Lastacaft?

Lastacaft (alcaftadine) Ophthalmic Solution is an antihistamine used to prevent itching in the eyes caused by allergies.

What Are Side Effects of Lastacaft?

Lastacaft may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • severe burning in the eyes, and
  • stinging or other irritation in the eyes

Common side effects of Lastacaft include:

  • mild and temporary burning/stinging/irritation of the eyes when you apply Lastacaft,
  • eye redness or itching,
  • runny or stuffy nose,
  • sore throat,
  • flu symptoms, or
  • headache.

A very serious allergic reaction to Lastacaft is rare. Get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching or swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Lastacaft

The dose of Lastacaft is one drop instilled in each eye once daily.

What Drugs, Substances, or Supplements Interact with Lastacaft?

Lastacaft may interact with other drugs. Tell your doctor all medications and supplements you use.

Lastacaft During Pregnancy and Breastfeeding

During pregnancy, Lastacaft should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Lastacaft (alcaftadine) Ophthalmic Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Description for Lastacaft

LASTACAFT® is a sterile, topically administered H1 receptor antagonist containing alcaftadine for ophthalmic use.

Alcaftadine is a white to yellow powder with an empirical formula of C19H21N3O and a molecular weight of 307.39.

Contains

Active: alcaftadine 0.25% (2.5 mg/mL)

Inactives: benzalkonium chloride 0.005% as a preservative; edetate disodium; sodium phosphate, monobasic; purified water; sodium chloride; sodium hydroxide and/or hydrochloric acid (to adjust pH)

Chemical Name: 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-imidazo[2,1-b] [3] benzazepine-3-carboxaldehyde

Structural Formula

LASTACAFT® (alcaftadine) Structural Formula Illustration

The drug product has a pH of approximately 7 and an osmolality of approximately 290 mOsm/kg.

Uses for Lastacaft

Purpose

Antihistamine

Use

Temporarily relieves itchy eyes due to pollen, ragweed, grass, animal hair and dander

Dosage for Lastacaft

Directions

adults and children 2 years of age and older:

  • put 1 drop in the affected eye(s) once daily
  • if using other ophthalmic products while using this product, wait at least 5 minutes between each
    product
  • replace cap after each use

children under 2 years of age: consult a doctor

HOW SUPPLIED

Other information

  • only for use in the eye
  • store at 15°-25°C (59°-77°F)

Inactive Ingredients

benzalkonium chloride 0.005%, edetate disodium, monobasic sodium phosphate, purified water, sodium chloride, sodium hydroxide and/or hydrochloric acid

Questions or comments?

1.800.678.1605

Distributed by: Allergan USA, Inc. Madison, NJ 07940. Revised: Aug 2022

Side Effects for Lastacaft

No Information Provided

Drug Interactions for Lastacaft

No Information Provided

Warnings for Lastacaft

For external use only

Precautions for Lastacaft

Do not use

  • if solution changes color or becomes cloudy
  • if you are sensitive to any ingredient in this product
  • to treat contact lens related irritation

When using this product

  • do not touch tip of container to any surface to avoid contamination
  • remove contact lenses before use
  • wait at least 10 minutes before reinserting contact
  • do not wear a contact lens if your eye is red

Stop use and ask a doctor if you experience any of the following:

  • eye pain
  • changes in vision
  • increased redness of the eye
  • itching that worsens or lasts for more than 72 hours

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away

Overdose Information for Lastacaft

No Information Provided

Contraindications for Lastacaft

No Information Provided

Clinical Pharmacology for Lastacaft

No Information Provided

Patient Information for Lastacaft

No information provided. Please refer to the WARNINGS AND PRECAUTIONS section.

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