Hypertonia: Increased tightness of muscle tone and reduced capacity of the muscle to stretch caused by damage to the motor nerve pathways in the central nervous system. Untreated hypertonia can lead to loss of function and deformity. Treatment can include physical and/or occupational therapy or medications. Injections of botulism toxin (botox) are sometimes used in the treatment for chronic hypertonia in cerebral palsy and other disorders. Also known as spasticity.